Running InterVar with updated database

[solcos]

Hello!

I am trying to run InterVar to get the ACMG 2015 from my VCF file.

I am using InterVar version 2.2.2 20210727 and Annovar from 02032025. The problem comes when I add to the config file, the updated database names for the annovar files, for example 'clinvar_2021050' for the 'hg38_clinvar_20210501.txt' file. When I run the command 'python3 Intervar.py -c config.ini', I get the next error:

'''
Error: the required database file /annovar/humandb/hg38_clinvar_20210501.txt does not exist.
Warning: Customized disease cutoff 0.01 in config.ini, not suggested as 0.005
Warning: The InterVar seems not run correctly, please check your inputs , options and configure file!
ERROR: The InterVar did not find the annotation result file from ANNOVAR!
ERROR: The name of annotation result file should be like test/test*.hg38__multianno.txt
'''
As you can see the script is trying to use the outdated version of the file and, of course, it is not there since I just downloaded the newest version. This happens for all the different databases I want to use the updated file.

Am I supposed to use the old version? Or there is another way to use newer databases?

Thanks in advance :)

[serge2016]

Same question, could you help, please, to update the databases?

[serge2016]

Similar to #98

[serge2016]

And similar to #94