diff --git a/src/current/v26.1/physical-cluster-replication-technical-overview.md b/src/current/v26.1/physical-cluster-replication-technical-overview.md
index 8a465f0175c..a82961f9c10 100644
--- a/src/current/v26.1/physical-cluster-replication-technical-overview.md
+++ b/src/current/v26.1/physical-cluster-replication-technical-overview.md
@@ -68,3 +68,11 @@ When a PCR stream is started with a `readonly` virtual cluster, the job will del
 After reverting any necessary data, the standby virtual cluster is promoted as available to serve traffic and the replication job ends.
 
 For details on failing back to the primary cluster following a failover, refer to [Fail back to the primary cluster]({% link {{ page.version.version }}/failover-replication.md %}#failback).
+
+### Multi-region behavior
+
+You can use PCR to replicate between clusters with different [cluster regions]({% link {{ page.version.version }}/multiregion-overview.md %}#cluster-regions), [database regions]({% link {{ page.version.version }}/multiregion-overview.md %}#database-regions), and [table localities]({% link {{ page.version.version }}/table-localities.md %}). Mismatched regions and localities do not impact the [failover process]({% link {{ page.version.version }}/failover-replication.md %}) or ability to access clusters after failover, but they do impact [leaseholders]({% link {{ page.version.version }}/architecture/glossary.md %}#leaseholder) and locality-dependent settings. Clusters replicating across different regions may also experience a slight decrease in performance due to longer replication times. 
+
+If the localities on the primary cluster do not match the localities on the standby cluster, the standby cluster may be unable to satisfy replicating locality constraints. For example, if a replicated regional by row table has partitions in `us-east`, `us-central`, and `us-west`, and the standby cluster only has nodes with the locality tags `us-east` and `us-central`, the standby cluster cannot satisfy the regional by row `us-west` partition constraint. Data with unsatisfiable partition constraints is placed in an arbitrary location on the standby cluster, which can cause performance issues in the case of a failover event due to latency between regions.
+
+After a failover event involving clusters in different regions, do not change any configurations on your standby cluster if you plan to [fail back to the original primary cluster]({% link {{ page.version.version }}/failover-replication.md %}#failback). If you plan to start using the standby cluster for long-running production traffic rather than performing a failback, adjust the configurations on the standby cluster to optimize for your traffic. When adjusting configurations, ensure that the new settings can be satisfied on the standby cluster. In particular, ensure that the cluster does not have pinned leaseholders for a region that does not exist on the cluster.
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